Kirby's Canvas Curse - Showed me the DS was more than a mere novelty and could produce truly fun and innovating games.
Osu! Tadake! Ouendan! - Showed me I could be addicted to a music/rhythm game and the music genre could branch off beyond just DDR/Guitar Hero clones.
Muramasa: The Demon Blade - Finally brought back that love for old school games and Action/Platformers I've been craving since Symphony of the Night. And improved on the style of gameplay and presentation dramatically.
Super Mario Galaxy - Made me actually like 3D Mario games and showed great promise for the Wii to come.
Company of Heroes - Added numerous innovations to the RTS genre that I've been waiting for since the days of Warcraft and Starcraft and evolved gameplay beyond simple 'micro' and 'farming for minerals'.