Bloodborne really thrived on its rather specific gameplay and it's lovecraft world with horrifying enemies and the near perfect atmosphere and music. So unless you want a really horrifying Zelda I guess not the best combo. Way more intresting for Metroid Prime.
As for Dark Souls which is closer to Zelda maybe. Building your silent protagonist the same way as a Dark Souls character and making gameplay really unforgiving might work. But the enemies should be less horrifying and it needs more exploration than any Dark.Souls game. I think a Souls like temple/dungeon would be best. Should be the hardest and darkest dungeon of the game with unique enemies which doesn't make use of any gimmicks and finishing this dungeon is only possible by being good with a sword and shield.
Please excuse my (probally) poor grammar







