The question is, why? What does it add to the game? They could theoretically give Link a whole backstory about being Transgendered and the difficulties of growing up transgendered but it just wouldn't make sense in a game like this.
Further, we already have an established canon and while Link is a more flexible character then most, such a change would have to be justified and that seems like it would mostly just detract from the game.
I am with Stan Lee on this idea. If you want LGBT characters in art, make them. Don't take established characters with established lore/backstory and throw that out the window to rebuild them.
Lastly, I think "trans" characters are the most difficult to do in a game scenario because the key point of being a transgendered person is not "I used to be a man", it is "I am a woman". Unless you turn a game into a character study (which is quite rare in gaming), the current state of a character is usually all that really matters. For all we know, 90% of game characters are transgendered but they just never went into their past...







