Nintendo made Mario what it is , Mario doesn't make Nintendo. They've pushed and promoted the Mario brands for decades into that household name we all know and love.
But if Nintendo was to loose Mario it would be a significant short term loss but they'd re-evaluate and push another brand maybe Zelda like kaz suggested or something totaly new.
If you take the Nintendo goggles off you'd realise the Mario the success of the mario brand isn't it's depth but it's penetration.