There's a reason RE4 was originally a Devil May Cry game. It went on to spawn more Evil May Cry's with 4 being the only acceptable one. At least there's Revelations?
Devil May Cry was originally Resident Evil 4. Capcom did a lot of experimenting for how they wanted RE4 to turn out.
As much as RE4 wasn't a real Resident Evil. It did lay the blueprints for games such as Hears of War and uncharted so it was a pretty important software release in its own right.