Super Mario Galaxy 2. Easily trumps NSMBWii right now but it might be harder once I've seen some more levels and coverage of the latter.

New Super Mario Bros for Wii. I sold my Wii in December and am already in the works of purchasing a new one.

L4D2......:)

The new Monkey Island

Only two The Last Guardians so far...

Let's make that three. I say The Last Guardian.

Followed by Agent, followed by a rather large gap, followed by Modnation Racers.

On a side note, anybody who thinks "the site is overrun with PS3 fanboys" needs to look here.

Super Mario Galaxy 2

Mario Galaxy 2, since that seems to be the only game from e3 I actually want.

Halo:Reach easily. Another top notch Bungie game is on the way.

I'd like to say MGS Peace Walker, but I don't even own a psp.

I'll go with The Last Guy then ... oh wait .... Guardian