WTF! I wanted to start the last disc of Lost Odyssey (great game btw) and my 360 won't read it! It's not the console, cause when I put in disc 3 it doesn't have any issues.

The disc is clean and has no scratches (I bought it new, and I just took it out of the (crappy) paper sleeve.

Anyone else had this? anyone know what I can do?

Try saving it to the hard drive.

This

^The xbox can't find it, so its unable to install. (I'm assuming).
Your best bet is to keep trying until it does show, and then install, but even then it may not be able to see the disc when verifying the installed version...

If you can't get it to work like that, then you'll probably need a new version.

It won't even read it, let alone save it to the hard drive. It doesn't recognize the game.

I always save my games to the HDD, especially LO, otherwise the loading times would be unbearable.

Shoot, forgot about that.  You might could call in a disc  replacement.

Hold it up to the light. Check for ANY small holes in the disc. They can be a mm wide and ruin the entire disc.

I suggest you not play the 4th disc unless you want to start hating the game. I absolutely loved Lost Odyssey until the 4th disc.

Why? I missed something or what?

In my opinion, the pacing completely fell apart by the 4th disc. Character development halted for the sake of shuffling your party through dungeon after dungeon, and it seemed like your characters were turned into cut-out superheroes.