Days of the Tentacle. Hands down no contest:

Thomas Jefferson: George says everyone should have a vacuum cleaner. What is a vacuum cleaner? No idea but if George says so.
Ben Franklin: Hoagie, one day I will name a invention after you.

Oh and Baldur's Gate2 is also cool.

Star Fox had the most classic quotes in any game I've ever played, like:
"Andross has ordered us to take you down"
"I...can't...lose..."
"Bow to the Great Androoooss"
Slippy: "You want a piece of me?" *8 seconds later* "Ahhhhhh!"
Here are some other ones I like:

"Un forastero!!!, Matano."- Resident Evil 4

"Rocky doesn't suck, you suuuck" -WWF War Zone

"....why don't you go suck on a monkey's nipple?"
"....you're nothing but a pimple on a donkey's ass!"
"What you think? I wipe a monkey's ASS with "what you think"!!!" All The Rock in No Mercy

Vince McMahon:
You know, that's something else again I've been meaning to talk to you about. What is this, "wipe the monkey's ass"? What is that??? I mean that's kind of a little....unordinary!? I won't say pervert, but this is strange! This is strange thinking!!! Because you have some sort of fixation with the rectal cavity!!-No Mercy again

What a great game..........

"This is Rupture Farms. They say it's the biggest meat processing plant on oddworld. I used to work here, well, I was really a slave, like all the others..." - Abe

From Oddworld: Abe's Oddysee.

"Tough day. Anyone else hungry?"

-Some random goon in Deus Ex after killing the player character.

I like you fernando lol...

I entered this thread to post pretty much what you posted in your OP.

Starfox 64 (or lylat wars as it is know in my country) has some classic quotes.

Wise fwom youw gwave!

^shit! that must be one of the first voices I heard on a console game.

edit..mmm I'm not sure now, did the master system version have that voice?

Barry:hat was a close one, a second late and you would of fit nicely into a sandwitch!
Jill: Really? Thanks!

Command & Conquer
Commando:
"Got a present for ya!"
"Shake it baby!"
"Ha ha!"
"CHA-CHING"

Duke Nukem
"What are you waiting for? Christmas?"
"Your face, your ass... What's the difference"
"Damn! Those alien bastards are gonna pay for ruining my ride"

I am Error.
-Zelda II: The Adventure of Link

The last metroid is in captivity. The galaxy is at peace.
-Super Metroid

You were almost a Jill sandwich!
-RE/REmake

Hey dudes, thanks for rescuing me! Let's go for a burger...Ha! Ha! Ha!
-Bad Dudes

Would you kindly...
-Bioshock