Some honourable mentions, now that others have reminded me of them:

Elizabeth, Bioshock Infinite

Kazooie, Banjo-Kazooie

Midna, Zelda Twilight Princess

Syrenne, The Last Story

Way to go, Bayo and Samus!

Yeah, Syrenne was extremely awesome. Her secret convo comparing her breasts with Calista (and kicking Zael's ass for spying on them) was hilarious.

I have The Last Story but never made it that far through. It's still on good old Mt. Pile o'Shame. :(

It isn't a long game, by RPG standards, so you should go back one day and finish it once and for all!

It's a real breath of fresh air to have the hard-drinking brawler be a young woman instead of a guy or a dwarf. Loved her sense of humour too.

And yeah, that scene's a classic. Also, if you sneak around the back of the inn, you can overhear a similar scene between the men comparing dick sizes. XD

Aqua from Kingdom Hearts.

Yeah, I remember that one as well. It was extra hilarious because it was mostly Dagran and Lowell having a friendly convo about their "tool", and then it was Yuri or someone else who entered and they went extra silent, hinting at him having much better measurements.

Not any part of a game specifically. It's the Mountain of Shame, where all the backlog is stacked.

Yeah, they compare Yurick's to a Muruk, a boss monster you fight later the size of an elephant. XD

Regarding Syrenne, another great scene is where she introduces you to the battle arena, but makes it sound like she's talking about a brothel to tease Zael.

Fem Shepard from Mass Effect, and Fem Hawke from Dragon Age 2 and Inquisition. Well written characters that don't lose cohesion despite all the player choice elements.

Hana from Fear Effect. Strong and determined.

Rynn from Drakan: The Ancient's Gate. Monster ass kicking dragon rider, what more can you say?

Brigitte (Rosy) from Valkyria Chronicles. Even though she starts out as the VC version of an anti-semite she does come around. And she's a fearless warrior.

Aerie from Baldur's Gate 2. Awesome mage and a lovely personality. And an Elf.

Merrill from Dragon Age 2. A beautiful irresistible mess who does blood magic, but with a good heart. And that Welsh lilt.

Ellie from TLOU. One of the best written characters in gaming.