I just hope all this talk of the ending won't turn into a spoiler filled internet come release. There are certain people who just love to do that:

Uncharted 4: A Thief's End – announced to be the final installment of Nathan Drake's adventures – is now finished and in final code, which means creative director Neil 'Curly Dragon' Druckmann has started getting feedback about what people think of the end of the game.

"I think people will discuss the ending. If focus tests are anything to go by, there will be some arguments about the ending," he told IGN during a recent A Thief's End gameplay event. "I'm excited. Indifference would be the worst thing. I would rather have people hate it than be indifferent to it. We'll see how they react."

Does that mean Nathan Drake is heading toward a final end? "Do you really want me to tell you? You don't really want me to tell you," Druckmann said, laughing, when asked point-blank if Nate will survive the end of the game.

http://uk.ign.com/articles/2016/04/04/uncharted-4s-ending-will-be-divisive

I hope its not a negative ending, nothing worse than having a serious you love and then do what I would call a Rosanne or a How I met your mother ending.

I bet Drake is gonna die. Or Sully. Probably Sully.

If i was going to bet on someone dying its sully.

Well, Sully dying wouldnt make for a controversial ending if its part of a good story. That's why my first guess was Drake, that would be a very bold move however improbable.

I think Drake won't die but will lose a limb, probably an arm.

Goodbye, Elena.

I can also see that as a possible option.

That's music to my ears! :D

I could see Sully dying, but I would personally be surprised if Nate or Elena did.