Deadly Premonition (Yeah, I know Curl's gonna lynch me for this one)

Dragon's Dogma (One of the best games I've ever played)

The last Story (Loved it more than Xenoblade Chronicles)

Resident Evil Umbrella Chronicles & Darkside Chronicles (One of Capcom's best love letters to its fans)

Ghost Trick (Just awesome)

Shadow Complex (Not as overlooked at the rest, but still, it didn't had the attention it should have. Best 2D Metroid from seventh gen)

Vanquish (No need to explain, right?)

These are the ones I can think of now, but I'm pretty sure I'll remember more.

No lynching here, I welcome differing opinions, it's why I make so many poll topics. :)

Go play Ghost Trick if you haven't yet!

I'll have to borrow a friend's DS, I'm never owned a handheld haha.

Resonance of Fate. The most innovative and crazy JRPG of last gen. Only I ever played that game. There will never be a sequel because people don't like new and interesting things. They only want old FF gameplay.

Last Story.

Fatal Frame.

Xenoblade Chronicles. - still not enough fame!!!!

Epic Mickey -- good platforming, great RPG integration, a love letter to Disney

Killzone Liberation -- arguably better than its console counterparts, deep and engaging gameplay

Folklore -- amazing sound and art direction, interesting controls, and a unique combat system 

Zack & Wiki: Quest for Barbaros' Treasure -- brilliant puzzles, challenging and imaginative

999: Nine Hours, Nine Persons, Nine Doors -- arguably the best story and storytelling of any video game, ever

Finally, someone else who likes this game!

I avoided it for ages cos of its critical mauling, and when I finally borrowed it on a lark, I loved it to bits. So underrated.

Hopefully the sequel can fix that. ;)