The .1 or .2 determines the number of subwoofer channels, which is separate ultra low frequency sound (<80hz) Subwoofer sound hardly has any directionality as the wall reflections make it impossible to tell where it's coming from. (The sound waves are 8 meters long at 20hz) Plus you feel it more rather then hear it. Multiple subwoofer channels only make sense when you go up to concert hall sizes.
As far as I know it has nothing to do with USB, but x.2 is pointless at home. x.1 is pointless too unless you have a decent subwoofer. (Not the ones that come with pc speakers which are not much more then regular bass extension) Multiple subwoofers can be useful to help negate dead spots from interference patterns with the walls, but giving them seperate audio tracks won't be noticeable in a home environment.
22.2, yup still not enough for Dolby Atmos. However the max for home theater receivers is 11.2 atm with Cinema DSP 3D digital audio processing. I used to have a 10.1 amplifier, never used more then 5 speakers with it though, not enough room! And I rather spend more on the quality of the speakers than quantity.







