I skipped this gen almost completely, with the exception of portable consoles and PC. But Wii U is almost bringing me back to my roots! It's looking nice, full of potential.
Animal crossing with the touch screen is a completely different beast altogether too.
3D Mario, with gorgeous graphics and level design.
Metroid - imagine what the touchscreen could do with Samus's visors.
And 2D Mario will seal the deal, as always.