New super mario bros Mii. Mario, luigi, my bother and me on the same screen!!

Hopefully Mario sales wise, but if I didn't really care about sales I would say Kirby! :)

If they make DKCR2, I'll be seriously tempted to buy it at launch. I woundn't mind Starfox either, and of course Metroid is always welcome.

 What would really throw Nintendo to the top of tops on the Pre-Order and FW Sales Charts would be to do a "one, two punch" sort of thing. They could come out with a 2D Mario and a new Wii Sports 3. They would make Wii Sports Bundle/Sell on shelf (Launch Title) and then have the 2D Mario out by October/EARLY November, that would sell Wii U's like madness! *Also they should then get out a Mario Kart 'U' around mid to late December*. And BOOM! A *billion seller! (and I think the Wii U will come out around September-SUPER early November.)

 *sarcasm. ;) *probably not going to happen.

Why would they do that when Super Mario World controls better?

Pik frickin min! I am tired of waiting, though I can now wait a little longer as I don't want it to be on the Wii.

I still think this is going to be the first hardware launch with a 2D Mario since the SNES.

I mean, it's possible that they'll use 2D Mario as a booster in case of emergency, and give us something else (like 3D Mario) if they think that the system will sell well enough on its own without it, but they said they learned from the 3DS. I hope that takes them in this direction.

SMB 6

Indeed.  I think there's actually a very good chance of Pikmin 3 being a launch game (or at least launch window).

A proper New Super Mario Bros sequel, but NOT WITH F***ING MIIS.