Since the Nintendo3ds is now the main home of the Monster Hunter franchise, I think it can become popular internationally, maybe even 'Pokemon level' popular... if Capcom plays their cards right. I mean look at the trailer and the epicness. Now imagine playing that with 3 of your buddies in the same room or online(if there is).
So here are some things I think Capcom can do to make the franchise a real success outside of Japan.
Market to the pokemon audience- If anyone is gonna play the multiplayer locally(the main appeal of the game), its the pokemon audience. Just needs to be marketed to the kids/folks properly. What kind of person doesn't like dinosaurs/giant monsters? There are lots of similarities between the pokemon and the MH franchises when you think about it.
A more fleshed out (or less grindy) single player- One of the advantages pokemon has above MH. I hope MH4 at least head in that direction.
Release a demo with four player support(local)- a quick way to have the 3ds audience see the value/fun of team-work when taking down a giant monster together. 1 area and one tough monster, everyone who owns a 3ds has access to it.
A Monster Hunter Cartoon- Gotta Hunt 'em all! Gotta Hunt 'em all!
Release the game outside Japan- this to, in my opinion, is very important.
Once they get the pokemon audience on board(or a good portion), It could spread beyond that audience because of the more universal appeal of giant monsters.
(And yes I know "taking over the world" is a bit.. extreme, makes a cool title tough)
Discuss
UPDATE: Famitsu details , Famitsu scans "The game's development scale is the largest in series' history" Better single player!
My 3ds friendcode: 5413-0232-9676 (G-cyber)