Good question, and one I feel I'm not qualified to properly answer as there's too many key ports on say SNES and Gamecube that I haven't played.
For me personally, based on what I've played, I found the Wii version of RE4 to be the definitive version of IMO the best game ever made thanks to its incredible IR-powered pointer aiming.
On Switch, Sniper Elite 3/4 were not only some of the best ports on the platform technically but the gyro controls really took the sniping to the next level where you actually had to hold your hands steady and carefully dial in your shot.
Ace Combat 7 on Switch is not only one of the best looking games on the console, but its locked 30fps is arguably preferable to the unstable uncapped performance on PS4/XBO.
Alien Isolation likewise one-ups the "big boy" consoles in image quality due to benefitting from more modern AA, and is a graphical showpiece for the Switch.
