I'm going to try this hint thing out.
50. A platforming series's very late jump to 3D.
49. A visual novel where branching paths are a mechanic.
48. A platformer where the toughest obstacle is a knee-high bump.
47. A rhythm sequel based on a rich musical library.
46. The oldest game in my Top 50, the first in a series well-represented.
45. A rail shooter where nobody gets hurt.
44. An action spinoff to an action-adventure juggernaut.
43. The 4th entry in a 4X series.
42. Early 2010's open world in an urban setting... no, not that one.
41. An RPG that was overlooked at release and has since become renowned.