Biggest System Sellers

[Salnax]

Ignoring the obvious Mario & Pokemon:

• Space Invaders (Atari 2600) - Was the best-selling game of all time in the early 80's, and is the main reason the 2600 sold more than a few million units.
• Donkey Kong (ColecoVision) - Was the main factor that made the ColecoVision outsell the Atari 5200, by simply being the best port of DK available.
• Xevious (Famicom) - Was actually the biggest seller on the Famicom before Super Mario Bros, and arguably helped sell the idea of third parties selling healthy numbers on others' console hardware in Japan.
• Tetris (Game Boy) - Outsold Super Mario Land and topped charts for months even in regions where it wasn't bundled.
• Street Fighter II (SNES) - This was what arguably made the SNES controller the template for most consoles' controllers going forward, by virtue of having 6 buttons.
• Doom (PC) - Is the reason why PC gaming is a big market.
• Myst (PC) - Sold the CD-ROM format on home computers.
• Ridge Racer (PlayStation) - A weird example, since it didn't sell THAT well. What it DID do was being a technically impressive launch title that convinced early adopters that the PS1 was a superior 3D machine compared to the Saturn (sorry Daytona USA).
• Virtua Fighter 2 (Saturn) - The game had 1.5 million pre-orders in Japan. The Saturn ended that year with only 2.2 million Saturns sold.
• Grand Theft Auto III Trilogy (PS2) - They're GTA. One of the biggest victories of the Xbox 360 was getting GTA4 as a same day multiplat, not even an exclusive.
• Halo 1/2/3 (XB/X360)
• Brain Age 1 & 2 (DS) - Although the DS had some other big hits, these games released around the same time as the DS Lite when the platform really took off.
• Monster Hunter Freedom series (PSP)
• Wii Sports (Wii) - Note that this game had a 40% attach rate even in regions where it wasn't bundled with the Wii.