I have doubts Metroid Prime 4 is a Switch-only game. It's going to end up being a cross-gen launch window title for the Switch 2 as well, like Twilight Princess and BOTW before it. If it was Switch-only I think they would have shown at least a real teaser trailer with some actual footage at this point. We've even gotten a few seconds look at that Princess Peach platformer which is a 2024 game, what exactly is it about Metroid Prime 4 that can't be shown at all even though it's been announced for several years now. Probably because they decided a while ago it was going to be a key Switch 2 launch window title.
If Switch 2 has some type of VR I wouldn't be surprised if Metroid Prime 4 is going to be one of the major showcase titles for it.