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Adenovirus probable cause of mysterious child hepatitis

Scientists and clinicians are now investigating whether there has been a change in the genetic make-up of the virus that might trigger liver inflammation more easily.

Another possible explanation is that restrictions imposed in the pandemic may have led to young children being first exposed to adenovirus at a slightly later point in their lives, leading to a "more vigorous" immune response in some.

Prof Calum Semple, who is an expert in infectious diseases at Liverpool University, said: "Adenovirus virtually disappeared during the Covid outbreak when there was reduced mixing and it has come back in a surge now."

He said other hypotheses are also being explored, including whether a recent Covid infection might be a trigger for the liver problems along with adenovirus. There is no link to the Covid vaccine. None of the currently confirmed cases in under-10-year-olds in the UK are known to have been vaccinated.

https://www.bbc.co.uk/news/health-61220518