I still think Animal Crossing is going to be the hydrogen bomb that blows the charts up. Smash, Zelda, Metroid, etc are games traditionally popular with men, but Animal Crossing is massive for both genders and will move some serious hardware because of it, in my opinion, even more than Pokemon. 2020 going to be nuts and we don't even know probably 90% of the games going to be released in it.
Both my oldest daughter and wife (who isn't a traditional gamer) love Breath of the Wild, so I would say that has changed this generation.
I agree with Animal Crossing. The Switch version is almost certain to become the biggest of the franchise. It also has a wide age appeal. It's the first game franchise I played extensively with my kids. So there's already nostalgia there for them with the game, similar to me and 2D Mario (since I grew up with SMB 1, 2, 3, and World).
It's also probably the first true casual console game - and when I say that, I don't mean games for retarded people (as some people in this forum tend to use the term), but games that encourage short sessions of gameplay over long periods of time.
I describe myself as a little dose of toxic masculinity.