Somebody's probably already said it, but when FFXIII releases, the PS3 userbase will be much larger than the PS2 userbase when FFX launched.
Also, there is a precedent that shows a single game can revive a dead system. Just look at Monster Hunter for the PSP. Before that game, Japan was the weakest region for the PSP and now sales there are equal to or greater than any other territory simply because of this one game. And arguably, the DS is bigger competition for the PSP than the Wii is for the PS3.
Anyway, this thread is dumb like the Kingdom Hearts threads. Can we just wait until we actually get a release date to talk about crap like this. A whole heck of a lot can change in the time between now and release.
My Top 5:
Shadow of the Colossus, Metal Gear Solid 3, Shenmue, Skies of Arcadia, Chrono Trigger
My 2 nex-gen systems: PS3 
and Wii 
Prediction Aug '08: We see the PSP2 released fall '09. Graphically, it's basically the same as the current system. UMD drive ditched and replaced by 4-8gb on board flash memory. Other upgrades: 2nd analog nub, touchscreen, blutooth, motion sensor. Design: Flip-style or slider. Size: Think Iphone. Cost: $199. Will be profitable on day 1.
