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Having serenaded Mario Galaxy for several pages, I should note my runner up is BOTW. I've talked at length about this before, but it's the first game in years that really inspired my imagination with the almost endless gameplay potential made possible by its physics and chemistry systems, and the way such an elaborate system was woven together into such a cohesive, organic, and intuitive whole. 

Other honourable mentions from me go to Ocarina of Time, Galaxy 2, and Metroid Prime.

Bet with Liquidlaser: I say PS5 and Xbox Series will sell more than 56 million combined by the end of 2023.