Twilight Princess was the first game whose level design truly blew me away, and using the wiimote for the sword and bow felt amazing at the time.
Wii Sports was a revelation. I still take it out to play every now and then.
Using the beam lasso in Metroid Prime 3 is still one of the most satisfying moments of any game I've ever played, also the amazing fps controls.
Being able to enjoy Resident Evil 4 thanks to the improved controls.
Mario Galaxy. Nuff said.
The whole Prime Trilogy repackaged with Corruption's controls. Better than the Gamecube's Zelda: Collector's edition.
Switching between swords and guns on the fly in Red Steel 2. So awesome.
The 1-2 rpg punch of Xenoblade and Last Story.
Skyward Sword is my favorite game of all time. Great 1-1 controls, great dungeons, great art, great music, and a story that actually motivated me to chase after Zelda.