Soundwave on 18 October 2016
I think if Nintendo can manage to get Final Fantasy, Dragon Quest, Madden NFL, FIFA, NHL (pretty please?), Star Wars, Ubi Soft stuff, and Call of Duty that would be pretty good on top of the standard 3DS type stuff that would be pretty good, but even that is probably asking for a bit too much, lol.
Grand Theft Auto, Red Dead Revolver, stuff like that probably isn't happening. I think getting EA on board (even if they aren't enthusiastic) is important because they have exclusive rights to things like the FIFA and NFL and Star Wars licenses. If Nintendo doesn't get them they are effectively locked out of those IP and there are plenty of kids/family audience types that love those games so not having those would hurt Nintendo.
