Hiroyuki Sawano x Metroid Prime: Would this work?

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Absolutely not. Sure, though two tracks are great, as are many of XCX's themes, but it only takes one piece of garbage like this

https://www.youtube.com/watch?v=vyA_BmX8dgs

to destroy the atmosphere completely, and a strong and pervasive atmosphere is one of the cornerstones of Metroid as a series.