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I've got to go with manga. There are way too many incredible anime that have come from normal-style manga to ignore.

However, visual novels and, surprisingly, 4-koma manga aren't that far behind. Though a lot of visual novels are fluff, Welcome to the NHK gives us an idea of the depth that visual novels can bring to the table. The amount of anime made from 4-koma manga would probably surprise a lot of people, as well. Yuyushiki, Azumanga Daioh, Monthly Girls' Nozaki-kun, Kill Me Baby, K-ON, and Aiura are some of my favorites.