Pokemon usually doesn't come that early.
I think Animal Crossing + Mario Galaxy 3 would be a strong 1-2 punch, one for launch day, one for the post-launch period.
IMO, Animal Crossing, Mario Galaxy 3, Luigi's Mansion 3, and Mario Kart 9 at minimum should already be well into development for the system and all aimed for a 2016 launch.
I dunno if they are going to go straight to Splatoon 2 which would require more time, but maybe a Splatoon: Special Edition or something could happen early in the life cycle too.