Would it be possible for the Wii U to run Zelda U at 60fps?

[shogunknight]

It definitely can, know that attaining 1080p 60fps is not just about the hardware but the devs choice to make it so. The game can be optimized to run at 1080p 60fps, 1080p 30fps, 720p 30fps or 720 60fps depending on the content the game devs have planned for it