Closer to current gen visuals and power to run the scope of full console games. Resolution doesn't need to be crazy high for handheld; a bit higher than a Vita is enough. Aside from that.. dual analogs, bigger face/D-Buttons, a single high quality capacitive screen (IPS or OLED), a video out function for TV output and finally no restriction region free console
Oh and better ergonomics. The OG 3DS was just uncomfortable to hold/play after a longish session.