Using the same gimmick of appealing to casuals? No.
They are gone thanks to Apple/Android and only value games at free/99 cents now.
Via some other avenue though? I wouldn't count them out. No one expected Donkey Kong, Super Mario Bros., or Pokemon to be break out hits.
Nintendo may be in a slump but don't ever forget they are a home run hitter are capable of crushing a baseball if they get the right pitch.
10 years ago it seemed impossible that Nintendo would ever see the NES/Game Boy peak ever again.
My personal feeling is if Nintendo becomes more like LEGO/Disney, which are large conglomerate companies and gets into things like animation on top of games, someday perhaps they can branch out to the point where they can eclipse even the Wii/DS era, provided they hit paydirt with a big enough new IP (or two) that becomes a phenomenon like Pokemon or Mario.
