Many years ago, I was playing a keyboard game with a friend, they were sitting next to me (we were holding hands) and my arm got really tired. We switched sides, and I realized I could play just as well with the other hand! I was completely surprised.
I write with my right, mouse and Wiimote with the left. I'm left eyed too. So I do a little of both.
For kinect it's usually which way the direction is - right for right choices, left for the left ones.
The two thumb stick of modern keyboard makes it pretty easy. In the Atari days you had to use the stick with your right and button with the left. (Unless you got a off maker one with extra buttons.)
Note: To figure out which eye is dominate - look at something say 10 feet away. Cover each eye and see which one makes the object move. If the object moves, that is your dominate eye. You are usually dominate in the same eye as your hand.







