Call of Grand Theft Angry Marios Smash Bros. 3 Alpha Plus EX Anniversary Edition for Wii U.
Seriously though, anything would be a big gun by now which isn't a remake. Be it Mario, Zelda or even F-Zero. The system is nearly one year old and got so little support, it's really sad to see.
Official member of VGC's Nintendo family, approved by the one and only RolStoppable. I feel honored.