Medicine will be greatly improved, things like AIDS and Cancer will be a "thing of the past", before a new disease pops up.
The World will be overpopulated and gas/oil/food will run low.
Petrol/Diesel engines will be a "thing of the past", with 95% of the developed nations running mainly on electricity.
There will be a homosexual Pope.
Humanity will begin to populate the moon.
Human cloning.
Huge developments in solar technology.
There will be people who are more machine than human. Bio-Implants will be the "in thing". No more need for steroids, instant muscle growth.
There will be a global currency, no physical money or cards, but done through nanotech
Nanotech.
I think some of that could happen.
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