I'ld only really be interested in first party collections. Mario Galaxy 1 & 2, Metroid Prime Trilogy remaster, and a Zelda Collection (Windwaker, Twilight princess, Spirit Sword?) would all be fairly cool.
I would LOVE a Smash Bros. Smash pack, which included Brawl and Melee upscaled with GOOD online support for both.
I might get a Mass Effect Triliogy..... I own one and two on different platforms (PC and Xbox) and don't plan on getting 3 for quite a while due to lack of time. Besides that though, I can't really see myself bothering with any third party offerings. Might be good for Wii only owners, though.