America HW up!

[Nintendogamer]

CGI-Quality said:

Software:

1		Heavy Rain	Sony Computer Entertainment	1	208,596	208,596
2		Wii Sports	Nintendo	171	133,702	32,080,002
3		New Super Mario Bros. Wii	Nintendo	15	113,456	5,736,562
4		Aliens vs Predator	Sega	2	90,692	297,644
5		BioShock 2	2K Games	3	89,723	622,981
6		Wii Fit Plus	Nintendo	21	82,747	4,702,338
7		Just Dance	Ubisoft	15	65,983	741,656
8		Call of Duty: Modern Warfare 2	Activision	16	55,586	6,637,474
9		Aliens vs Predator	Sega	2	55,275	183,321
10		Wii Sports Resort	Nintendo	31	52,597	5,913,865
11		Call of Duty: Modern Warfare 2	Activision	16	42,684	3,616,254
12		Endless Ocean: Blue World	Nintendo	1	42,399	42,399
13		BioShock 2	2K Games	3	38,041	261,567
14		Mass Effect 2	Electronic Arts	5	36,784	1,113,584
15		Mario Kart Wii	Nintendo	96	36,221	9,386,622
16		Dante's Inferno	Electronic Arts	3	35,977	236,035
17		Dante's Inferno	Electronic Arts	3	34,690	224,109
18		New Super Mario Bros.	Nintendo	198	27,245	8,176,184
19		Darksiders	THQ	8	26,032	274,294
20		MAG: Massive Action Game	Sony Computer Entertainment	5	23,886	396,470
21		Mario & Sonic at the Olympic Winter Games	Sega	20	22,230	1,251,420
22		Mario & Sonic at the Olympic Winter Games	Sega	20	21,413	938,111
23		Sonic & SEGA All-Stars Racing	Sega	1	20,498	20,498
24		Wii Play	Nintendo	159	20,120	13,981,520
25		Yu-Gi-Oh! 5D's World Championship 2010 Reverse of Arcadia	Konami	1	19,841	19,841
26		Mario Kart DS	Nintendo	224	18,794	6,906,425
27		Assassin's Creed II	Ubisoft	15	18,463	2,042,542
28		Assassin's Creed II	Ubisoft	15	17,869	1,382,976
29		Darksiders	THQ	8	16,904	367,531
30		Cabela's Big Game Hunter 2010	Activision	22	16,553	850,197
31		EA Sports Active	EA Sports	41	16,103	1,572,049
32		Tropico 3	Kalypso	2	15,427	39,643
33		Call of Duty: Modern Warfare: Reflex Edition	Activision	16	14,863	675,102
34		LEGO Batman: The Videogame	Warner Bros. Interactive	75	14,541	1,509,176
35		NBA 2K10	2K Sports	21	14,472	666,976
36		Sonic's Ultimate Genesis Collection	Sega	55	14,377	421,001
37		Pure	Disney Interactive Studios	76	13,702	1,332,983
38		The Biggest Loser	THQ	21	13,684	532,545
39		Gold's Gym: Cardio Workout	Ubisoft	49	13,606	605,313
40		Skate 2	Electronic Arts	58	13,443	707,278
41		Deadly Premonition	Ignition Entertainment	1	13,409	13,409
42		White Knight Chronicles: International Edition	Sony Computer Entertainment	4	13,214	141,339
43		God of War Collection	Sony Computer Entertainment	15	13,113	634,650
44		Uncharted 2: Among Thieves	Sony Computer Entertainment	20	13,011	1,393,217
45		Dora the Explorer: Dora Saves the Mermaids	2K Play	121	12,774	652,909
46		Madden NFL 10	EA Sports	29	12,431	2,226,077
47		Skate 2	Electronic Arts	58	12,042	305,566
48		Game Party 2	Midway Games	73	11,940	885,800
49		My Fitness Coach	Ubisoft	65	11,894	916,062
50		Super Mario 64 DS	Nintendo	275	11,773	4,150,467

 

I've added Heavy Rain in the top to celebrate it's release and selling the most.