1. Super Mario Galaxy (aka Game of teh Evar)
2. The Legend of Zelda: Twilight Princess
3. Okami
I know it wont count, but here's 4 through 10, just because I feel bad leaving these awesome titles out of the picture.
4. Super Smash Bros. Brawl
5. Metroid Prime 3: Corruption
6. Fire Emblem: Radiant Dawn
7. Resident Evil 4: Wii Edition
8. Guitar Hero III: Legends of Rock
9. Mario Kart Wii
10. No More Heroes