Failure depends on the goals. I'll go by what I think are the major goals of some games:

Metroid: Other M. I think they want to expand the Metroid audience, and possibly make it sell in Japan. I think it will fail at this.

Gran Turismo. I think this game is being positioned as a momentum builder* for PS3. I think it will fail at this.

Driver. I think they want to sell like the original. It won't.

*I'm going to use the phrase "momentum builder" in place of "system seller" to avoid semantic arguments

Fail in terms of sales? NMH2, Dante's Inferno

MAG, didn't really like the aiming and I just didn't think it was fun.

Alan wake, something bout that game makes you think its gonna fail big time

Alan Wake

Heavy Rain in the short term, Halo 9 or Call of Duty 21 in the future...whichever comes first (at some point ppl gotta get sick of fps)

@rap : yeah actually it happened to me long ago. Please give us new games, new ideas.

I'm bored with FPS...

I believe Epic Mickey will fail sales-wise.

Alan Wake might fail sales-wise, giving it's KZ2 like dev-time

Alan Wake, Heavy Rain, FFXIII (X360), White Knight Chronicles.

FFXIII for the 360 only.

HEAVY RAIN for the PS3.

NO MORE HEROES 2 for the Wii.