Beyond the Sky from Xenoblade Chronicles always brings a tear to my eye; such a beautiful song to conclude such an unforgettable journey

If you have a Wii and never played Lost in Shadow. Go get it. 

Also one of the best Wii games no one played. Very emotional game. Fragile Dreams. Does have a US version

This was accomplished on SNES with the very first Tales game btw. 

Amen, Amano Tsukiko's songs for the Fatal Frame series are amazing

Good Riddance from Hades
Edge of Dawn by Fire Emblem Three Houses

Alphecca ~Prayer of the Gyre Melody~ from Another Eden
https://youtu.be/TAylZtrlpr8

Build That Wall from Bastion
https://youtu.be/o3SZee4YZX8

Cara Mia Addio from Portal 2
https://youtu.be/tL_TFXbSnLY

Children of the Elder God from Alan Wake
https://youtu.be/7M1k1tgq87g

Cosmic I from Psychonauts 2
https://youtu.be/Rl4OY6H7PJY

Double Agents from Rocketbirds
https://youtu.be/Gg3GLzgsWsE

Dragonborn from TES Skyrim
https://youtu.be/813-3iL5OsE

Fate Runners from Eiyu Senki
https://youtu.be/joY-EATQtFg

From Dawn to Dusk from Endless Legend
https://youtu.be/Ew01HTfGhRQ

Illuminate Me from Rocketbirds
https://youtu.be/L8EBS_FJuLw

KUNA! Itzaland! from Infinity Nikki
https://youtu.be/-xcvurhPO78

Lay Down Your Arms from The Last Federation
https://youtu.be/AFFWXu1p2GQ

Lullaby of the Manifold from Warframe
https://youtu.be/f9NIGKDYucM

Mercenary from Batman: Arkham City
https://youtu.be/ZPRVKNc97ws

Never More from Persona 4
https://youtu.be/SXYdgfXyYqs

PARTY OF YOUR LIFETIME from Warframe
https://youtu.be/YtF6jiLxc88

Reach Out To The Truth from Persona 4
https://youtu.be/Mk0A5uFoG3c

The Red Queen from SteamWorld Heist
https://youtu.be/Q19JOcvhFvA

Sleeping In The Cold Below from Warframe
https://youtu.be/-EtOAaK19bA

Stifling Song from Another Eden
https://youtu.be/NBsDkrctN5I

Super Sonic Racing from Sonic R
https://youtu.be/qoNHGngO65U

Want You Gone from Portal 2
https://youtu.be/dVVZaZ8yO6o

We All Lift Together from Warframe
https://youtu.be/mPTCq3LiZSE

^Xenogears again