I thought I'd played them all but I guess I missed Nomad Soul. Even so, in still pretty confident when I say Detroit. It has a truly compelling narrative that really kept me engaged. It's also the best looking game I've ever played.
Omikron is very different game to everything else they made, and it might seem quite strange, especially for people that got into QD games with Heavy Rain - it's an action-adventure with elements of FPS and fighting games, with so-so story, but really fun world building. Not flawless by any means, but it still remains only QD game I really liked to this day (though I haven't played Detroit) and one of my all time favorites...despite its flaws.
Unfortunately, I don't think QD will ever make any game like it, they completely shifted to different genre with Fahrenheit, and then again with Heavy Rain, so more or less it was one time thing (though sequel was in the work at one point).