Overall: PS4+3DS

It's the 2 systems that has the most support. The Wii U is dead and alot of Wii U games you can find almost the same on the 3DS (ie. 2D mario, 3D mario, Mario Kart, Smash etc..) Heck 3DS even has new Zelda games that the Wii U can only dream of lol

I say this but I'm not a big handheld guy anymore (just how my lifestyle is). I have a PS4+Wii U and it's probably the best combo for me. I enjoy the Wii U for the couch-coop games (especially Mario Party). I have alot of friends over and we just have a blast.

Yep, I agree. That's my combo right now, the reasons are already stated on OP. I could afford a XB1, but owning both Wii U and PS4 I feel like this would be a waste. I'm not saying XB1 is bad or anything, is just that it would be a waste of money/time to get it given that I have access to most multiplat games + Wii U's exclusives. But I can see someone with the combo XB1 + Wii U extremely satisfied as well.

Is it though?

I'd say it's a great combination, aided in particular by the Wii U's off-screen play function, which means that there have been no arguments when both consoles have been in simultaneous demand.

PC + Wii U. And every generation to come PC + Nintendo Console. But if it had to be console only, then always Sony + Nintendo. Just know the + Nintendo to the combination is what makes it complete.

It all comes to personal taste, i dont think there is The Best Combo.

It depends on the person really. Not everyone likes Nintendo games, or the other games Sony and MS get. I would say there is no best combo, unless we're talking about owning all of them o:

PS4 + Wii U is good but this gen PS4 + NX might be better especially if it's backward compatible or if they port many of the U games to it.

PS4 + PC is also good.

But personally I'm going with PS4 + PSVR this gen as long as the thing doesn't cost €500.

Best combo is PS4 + Vita.

Wii U+PC Pre 2016
Wii U+ PS4 post 2016

I've actually preferred Xbox One's exclusive's up until now.