Pokémon Z

So far Uncharted 4 unless there is a new gen pokemon

Well since there are only console exclusives in the poll I'll probably go with Street Fighter V since it's on two platforms.

I want to say Pokemon Z but SFV has two platforms combined for a single game so sales like that are likely to be higher, Gears could have managed if MS decided to get fof their ass and port it to PC, dunno why they are even bothering with the first one which they still haven't ported over.

Uncharted 4 will have time to hit second wind during holidays and likely bundles combined with PS4's growing user base.

Uncharted 4 will cross 10 million mark by 2016.

I think it is between Uncharted 4 and SFV personally.

So far the belief is that Uncharted will get this, unless Pokémon releases. I'd agree with that too, but don't underestimate Street Fighter V people, this franchise sells a lot and it's on PC as well. I think it will be a close call.

That's a tough one actually. Zelda, Twilight Princess HD, Uncharted, and Horizon Zero Dawn all have strong arguments on this. Twilight Princess won't sell as fast as Zelda U, but has the benefit of more time. But it's also hampered by not being a super impressive overhaul.

Uncharted and Zelda U have the obvious argument of being their respective console's juggernauts with a lot of hype already built up.

Horizon Zero Dawn has the potential to go really huge BUT - and this is a big but - that all depends on Sony's commitment to hyping it up. If they go all Destiny on it, it could be the winner here. If not, probably not.

^ this.

Oh, we're counting handhelds....

In that case, if there's a new mainline Pokémon game, that will win. most without a doubt.