I'll be curious if they recast everyone to try and keep it going, or figure at this point Marvel can put any hero out and make money.  Who do they have left that hasn't had or isn't getting a movie?

I don't know much about comics, so I can't answer that. Marvel is already using Daredevil and other characters (Jessica Jones, Daisy Johnson/Quake) in TV shows.

At least I hope they let Spiderman rest for a while before rebooting it, again.

Since Guardians of the Galaxy opened up the movie universe to a much more cosmic scale, literally dozens of characters are available from that angle alone.

I wouldn't mind them doing a New Avengers style more street level team. Spiderman, Luke Cage, Wolverine (if rights can be worked out) and those sorts of guys. Alternatively, they could go with the style of Hickman's run and focus on more powerful characters dealing with cosmic level threats.

He is going to be Civil War so sort of a reboot and they have a stand alone movie planned down the road.

I doubt X-Men will be in Marvel for another decade at least. Inhumans are the "mutant" equivalent in Marvel movies.

Probably not, but I also didn't think it would happen with Spider-man.  Especially with the face of their franchise leaving, Fox could use a boost.  Letting characters appear in two movies could be mutually beneficial.

And, as much as Marvel has tried in the comics, they haven't been able to make Inhumans a thing.  Without massive changes to the Inhumans, they're not going to be anywhere close to a replacement to the X-Men.  Humans are a weird race that are way closer to aliens than they are to humans.

Fox seem more entenched than Sony.  Only way I can explain Fantastic Four failure and them planning another one already.

Well, Sony was planning an Amazing Spider-man 3, Sinister Six, and supposedly an aunt may spinoff.  Of course, Amazing 2 wasn't nearly as much of a failure are FF, but just because a sequel is being planned doesn't mean that it will happen.

Earth's Mightiest Heroes... flying around in space? No thanks, that run was awful. Leave the space stuff to Guardians.