The plural of anecdote is not data. Anyway, going by sheer sales numbers, the systems are best known for:

NES: Super Mario Bros, Duck Hunt, Super Mario Bros 3
SNES: Super Mario World, Donkey Kong Country, Super Mario Kart
N64: Super Mario 64, Mario Kart 64, Goldeneye 007
GameCube: Mario Kart: Double Dash, Super Smash Bros Melee, Super Mario Sunshine
GB: Pokemon Red/Blue, Tetris, Pokemon Gold/Silver
GBA: Pokemon Ruby/Sapphire/Emerald, Pokemon FireRed/LeafGreen, Mario Kart Super Circuit
Genesis: Sonic the Hedgehog 2, Sonic the Hedgehog, Mortal Kombat
DreamCast: Sonic Adventure, Crazy Taxi, NFL 2K
PS1: Gran Turismo, Final Fantasy VII, Gran Turismo 2
PS2: Grand Theft Auto: San Andreas, Gran Turismo 3: A-Spec, Grand Theft Auto: Vice City
XBOX: Halo 2, Halo, Tom Clancy's Splinter Cell

And the current gen is best known for (at the moment):

Wii: Wii Sports, Wii Play, Super Mario Galaxy
DS: Nintendogs, Pokemon Diamond/Pearl, New Super Mario Bros
360: Halo 3, Gears of War, Call of Duty 4: Modern Warfare
PS3: Motorstorm, Call of Duty 4: Modern Warfare, Resistance: Fall of Man
PSP: Grand Theft Auto: Liberty City Stories, Grand Theft Auto: Vice City Stories, Midnight Club 3: Dub Edition

YES!!!
DUH!!
OF COURSE IT IS THE MOST ANTICIPATED GAME!!
its y ppl. get the wii

b.c of brawl