Maybe if Kratos focuses his rage on a different mythology, like Persian it could work, because there really isn't much left for him to destroy in the Greek tradition. He's already killed all the major gods and most of the ancillary ones including the Titans, defeated its greatest heroes outside of those from the Trojan War (which could be an interesting setting, but I dunno), not only defied but killed destiny in the sisters of fate, hell he's beaten the furies twice, once a physical manifestation of the traditionally esoteric furies in Erinys, and then the furies more seen in drama in the sisters from Ascension. They were already scraping the bottom of the barrel with the psp games and ascension, there's really no where else to go within the confines of Greek mythos at this point.