I'm going to list my top 5 most anticipated on each platform, cause I can't really mention one without mentioning the others:
(I tried to avoid mentioning the games that are coming out multiplatform)
PS3-
1. Ratchet and Clank: Tools of Destruction
2. Little Big Planet
3. Heavenly Sword
4. Lair
5. Meta Gear Solid 4: Guns of the Patriots
This list is taking into consideration that FF XIII doesn't come out in 07.
PSP-
1. God of War: Chains of Olympus
2. Final Fantasy Vii: Crisis Core
3. Castlevania: Dracula X Chronicles
4. Final Fantasy Tactics: The Lion War
5. Monster Hunter Freedom 2
DS-
1. Ouendan 2 (replace this with EBA 2 if they decide to make that)
2. Spore
3. Zelda: Phantom Hourglass
4. It's a Wonderful World Remix
5. Final Fantasy XII: Revenant Wings
Wii-
1. Super Mario Galaxy
2. Super Smash Bros. Brawl
3. No More Heroes (yes, a 3rd party game on the Wii, who knew?)
4. Guilty Gear XX: Accent Core
5. Manhunt 2
360-
1. Mass Effect
2. Bioshock
3. Fable 2 (if it comes out in 07)
4. Blue Dragon
5. Too Human