Well, some confirmation on games like Ace Attorney v Professor Layton and Ace Attorney 5 would be nice. I don't know if they did yet, but a specific date on Paper Mario, and maybe a new Zelda on the 3ds, one can only hope.
As far as the Wii U is concerned, do you think Pikmin 3 & Mario Bros U will be good system sellers? The ports are just ports. People who already have the game probably won't get them again for the Wii U, or be convinced to buy it.
If anything, the conference taught me something valuable, when a new console is set to released, get all the casual fun stuff out of the way first. To me, that's the initial foundation for long term success, and for subsequent years/E3s the focus will be on core games and franchises. So, I think when next-gen xbox/ps comes out, their presentation will be much the same, casual glory, and the following year actual core games.
Right now though, I think the Wii U is a strong frontrunner. I'm basing this off how great Pikmin 3 looks, but once people have a stronger hand on the technology I expect some great titles and new IPs from Nintendo and 3rd Parties. If anything, I hope they have enough to fill the gap between after Xmas and 2013 summer.