Yeah Uncharted for me, but it was a close call. I wasn't even thinking of getting InFamous but it was bundled with PS3 when I bought it so I figured what the hell, I'll give it a crack. I'm so glad I played it. But there's something a bit special about Uncharted.

Could be that I end up liking InFamous 2 better then Uncharted 2 though. Uncharted 2 is better than Uncharted 1, but not by a huge margin. If InFamous 2 blows InFamous 1 out of the water then I think InFamous 2 will be the best of the 4. Still none of them beat Demon's Souls or Valkyria Chronicles for awesomeness.

ooo its hard and we all know Uncharted 2 is one of the best sequels going around and can be regarded as the best sequel ever (and i been the number 2, and not the rest after that) 

 No game in an long time managed what uncharted 2 did and improve on everything and at the same time keep the core of the orginal which to give credit to naughty dog, Extremely hard to do. 

I believe Sucker Punch is trying to pull the same thing off and i hope so with infamous 2 

now for Uncharted V Infamous. Ummm i liked them both but i give it to Uncharted since i am bias as uncharted 2 is the best single player game i have played since cod4, portal, GTA San Adreas and GTA Vice city. 

inFamous > Uncharted: Drakes Fortune, but I like both a lot.

I really liked Uncharted, but I only played it once. I've played Infamous three times now and I'm actually thinking of putting in a fourth play through. The mechanics are just so fine tuned and fun that they never get old. I can't wait for Infamous 2 and I really hope it gets more attention and sells more, Sucker Puncher deserve to be put on a pedestal for once.

In my opinion Uncharted is far better than Infamous. (Story, Characters and Gameplay). Infamous was interesting for a few hours and my first playthrough was ok. During the second Playthrough (evil) i started to hate that game.The Characters are lacking (Zeke...), I didn't like the storytelling with the comic style and the morale system totally broke it. Halfway through my evil Playthrough I was about to throw the game out of the window. My hunger for the Platinum won eventually but it felt really disgusting to finish that game. If InFamous 2 also has this forced evil playthrough for the Platinum the Series is dead for me, no matter how good the game will be.Somehow I feel those moral systems were introduced to allow ppl to play in more violent ways and at the same time give the publisher the opportunity to say that the game sanctions those violent actions and they want to show the gamers how immoral such behavior is. But those sanctions are laughable. In GTA 4 you can kill hundreds of Cops and Innocents and then just reload. In Oblivion you can turn autosave off and slaughter a whole village. etc. There is no real penalty for being evil. So in my opinion these moral systems are a real bad development...  

Edit: And Infamous is Open-World...Big Minus Point, since the Story always suffers greatly from Open-World Structure --> Sidequests are simply boring and repetitive

my thoughts exactly.

Got platinum in both of them.  They were both great, but if I have to choose then I would say Uncharted.

Open world games will ALWAYS beat linear games, so Infamous