I have a long list of expectations, some of the major ones are:
3DS info, with big games from Nintendo and Sega. I'm curious to see how they are going to show off the 3D functionality through video.
Zelda Wii, I'm curious to see how it differs from recent Zeldas, and I'm hoping for more of a return to the more old school arcade style Zelda.
Vitality Sensor - how exactly does this thing work with games and what game will use it. What will Wii Relax be like.
Hoping for confirmation on that Goldeneye Remake rumor.
Zangeki and Tales of Graces localizations. These are two of my most anticipated Wii games thus far, now that Galaxy 2 has been released, and they still aren't even confirmed for America.
More motion plus support, maybe some new established franchises that use it like Pikmin, Kid Icarus, Kirby, etc. Hopefully a new ip or two that uses it. Nintendo needs to show they are serious about motion plus.