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Sixth mass extinction is going on. But life has survived worse.
As for humanity, I'd say it's 50-50 can we reach for other habitable planets before making this one inhabitable.
I imagine this century will see something (in some ways) worse than last. Just a civil war in China or India could kill more people than WWII. Not to mention sending out tens of millions of refugees.
I don't think AI is something to worry about, humanity is still much bigger danger to itself.